Ingredient news
Short, source-led updates on PS, phospholipids, supplement regulation, research, and functional ingredient markets.
News briefs
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FDA proposed making GRAS notifications mandatory for substances used in human and animal food, replacing the current voluntary program, with comments due December 9, 2026.
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China's national standard GB/T 46804-2025, in effect since July 1, 2026, defines how phosphatidylserine content is measured in beverages, confectionery, convenience foods, and dairy products.
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China's non-GMO liquid soya lecithin market strengthened in July 2026, with FOB Tianjin prices up 2.1% month on month to USD 1,200 per metric ton.
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UNC researchers report that long-term choline restriction in mice remodeled liver lipid metabolism and drove insulin resistance through a CD36-ETNPPL regulatory axis.
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A Fujita Health University mouse study found that soy-derived lysolecithin LPC70 lowered high-salt-diet blood pressure and improved social and memory deficits.
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Two exploratory randomized trials of a standardized Ginkgo biloba extract combined with phosphatidylserine reported memory and reaction-time signals and mood improvements.
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A prospective cohort study in the American Journal of Clinical Nutrition found choline source and solubility were differentially associated with dyslipidemia risk, with gut microbiota as a key modifier.
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Danone Research and Innovation and the University of Lyon found that larger, milk phospholipid-coated lipid droplets were digested and absorbed differently than standard formula droplets in vitro.
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Researchers developed soy lecithin nanoliposomes encapsulating Echinacea purpurea extract and showed the formulation inhibited bacteria and preserved quality in a chicken meat model.
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Korean choline alfoscerate drugs failed the primary endpoint in a clinical reassessment for mild cognitive impairment, putting reimbursement and clawback outcomes in focus.
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A randomized study in 32 enterally fed preterm infants found choline chloride, choline bitartrate, GPC, and egg phosphatidylcholine all raised plasma choline after 48 hours, with GPC acting fastest.
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FSANZ approved milk fat globule membrane-enriched whey protein concentrate as a nutritive substance in infant formula products, and Arla says the decision gives its Lacprodan MFGM-10 exclusive Australian commercialization rights for at least 15 months.
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A Journal of Dairy Science study found fluidized bed drying kept whey protein phospholipid concentrate closer to native protein structure and preserved more xanthine oxidase activity than spray drying.
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A 4D lipidomics study found the largest phospholipid and ganglioside losses during initial milk centrifugation and additional composition shifts during churning, coagulation, and evaporation.
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A food science study reported that the highest-phosphatidylcholine sunflower fraction produced the smallest oil droplets and strongest interfacial stability in model ice cream.
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Researchers built high-internal-phase emulsions with sunflower lecithin, whey protein isolate, and sodium caseinate that stayed stable under heat, salt, and pH stress while improving beta-carotene bioaccessibility.
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Kirin and Blackmores said new citicoline-based cognitive support products will begin rolling out in Australia and New Zealand from late July 2026.
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A new adult meta-analysis reported modest reductions in total cholesterol, LDL cholesterol, apolipoprotein B, and the total-cholesterol-to-HDL ratio after short-term intake of bovine-derived MFGM or milk polar lipids.
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A Food & Nutrition Research study found larger sleep-quality and mood improvements after three weeks of higher-dose Melissa phospholipids in adults with emotional distress.
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A two-center observational cohort associated an oral citicoline combination with improvements in executive, memory, and mood measures in prodromal dementia and early Alzheimer-type decline.
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A pediatric short bowel syndrome analysis found low plasma choline, betaine, and phosphatidylcholine levels, linking lower choline status with liver-steatosis risk.
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A 12-week placebo-controlled study in Japan reported higher upper-arm skin hydration after daily dairy-derived sphingomyelin in healthy women.
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A crossover study using matched high-fat dairy spreads found no acute postprandial triglyceride advantage from intact or disrupted milk fat globule membrane versus a comparator without MFGM.
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Kyowa Hakko USA said Mintel and Black Swan Data identified Cognizin citicoline as a functional ingredient to watch, citing growing use across beverages, energy formats, and supplements.
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Lekithos introduced a sunflower lecithin granule format aimed at dry-format use, adding another non-soy phospholipid option to the supplement and functional-food market.
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O Positiv launched its first prenatal supplement, combining choline, omegas, iron, probiotics, ginger, and vitamin B6 in a single daily formula.
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A randomized clinical study reported stronger load-related leg blood-flow responses and lower aortic stiffness after four weeks of oral phosphatidylserine in adults with type 2 diabetes.
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A controlled infant-formula trial found no measurable body-composition advantage from large milk phospholipid-coated lipid droplets enriched in dairy lipids during the first two years of life.
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A recent review says DHA supplied in phospholipid-rich formats can deliver higher intestinal bioavailability than standard triglyceride fish-oil supplements, while also raising cost and formulation tradeoffs.
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A 2026 review argues that choline deficiency may remain a meaningful neural-tube-defect risk even in folic-acid-fortified markets, keeping phospholipid-linked prenatal nutrition on buyers' radar.
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A placebo-controlled human trial testing five dietary emulsifiers, including soy lecithin, reported microbiome-related shifts and lower short-chain fatty acids but little change in inflammation endpoints.
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A new narrative review calls choline an underused neurocognitive nutrient, linking prenatal intake gaps and limited human trial depth to a need for stronger formulation and clinical planning.
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EFSA's latest novel-food opinion says L-alpha-GPC made from soya phospholipids is safe for food-supplement use at the proposed maximum intake, adding a fresh regulatory reference point for choline suppliers.
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SmartyPants says its new Prenatal Plus Multivitamin Capsules deliver 480 mg of choline per daily serving, giving buyers another current read on how prenatal brands are increasing choline inclusion.
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BEVIMI's new Uno Protect launch packages phospholipid-form omega-3s from Norwegian herring roe into a shelf-stable liquid shot, signaling continued premium interest in complex brain-lipid systems.
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Sports Research says its Costco footprint now covers 10 wellness SKUs, including a krill-oil line built around phospholipid-bound omega-3s, choline, and sourcing transparency.
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FDA's 2026 Human Foods Program agenda says final guidance on NDI safety and identity information is due this year, giving ingredient suppliers another reason to tighten master-file style documentation.
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FDA's foods regulations agenda now lists a July 2026 proposed rule on when an ingredient is not excluded from the dietary supplement definition, giving ingredient developers another signal that category-boundary questions are moving from discussion toward formal rulemaking.
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A randomized trial in children with ADHD or subthreshold symptoms found the highest-dose PS plus DHA formula outperformed placebo and lower-dose comparators on multiple attention and inhibition measures.
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A 10-day trial in professional football players associated a taurine-caffeine-PS stack with better locomotor output, reaction time, and selected technical indicators, though the paper notes PS-specific attribution remains unresolved.
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A pilot imaging study found oral choline changed working-memory-related brain activation and connectivity in postmenopausal women, even though measured task performance did not differ from placebo.
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A temporal cohort study associated infant formula with added bovine MFGM with improved myelination in motor-related brain regions and better gross and fine motor scores.
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Bobbie says its updated organic whole-milk infant formula rolled out across Target with positioning around MFGM, DHA, and choline, highlighting how complex lipid systems continue to shape premium formula design.
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Standard Process says its Spirited Paw Healthy Mind launch combines phosphatidylserine with B vitamins, vitamin E, and MCT oil, extending PS use into aging-dog cognitive supplements.
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A new review argues that choline's immune effects depend partly on form, with phosphatidylcholine and sphingomyelin highlighted as meaningful contributors to immune development and inflammation-related responses.
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A Food Chemistry study reports that egg lecithin improved ultrasound-assisted egg-yolk-granule emulsions up to a threshold, after which excess lecithin displaced proteins and weakened interfacial stability.
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FDA has scheduled a public meeting on dietary supplement innovation and the scope of dietary ingredients, keeping U.S. compliance strategy and document readiness in focus for ingredient suppliers and brand teams.
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NIQ says South Korea's online cognitive-enhancement segment for Gen X posted sharp growth, with phosphatidylserine among the fastest-rising ingredients in the category.
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Golden Key Ingredients has introduced PSgold, a powdered sunflower-derived phosphatidylserine positioned for capsule, tablet, and powdered-mix formulations.
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O Positiv says its new MENO Brain product uses phosphatidylserine in a menopause-focused brain-fog concept, adding another mass-retail demand signal for cognitive-positioned ingredients.
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Life Time's new LTH Dream formula includes phosphatidylserine alongside magnesium, pharmaGABA, and other sleep-support ingredients in a melatonin-free format.
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A 2025 randomized trial of sunflower phosphatidylserine in healthy children found no significant overall differences on primary or secondary outcomes, while suggesting lower-performing subgroups may warrant further study.
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A randomized placebo-controlled trial in Chinese older adults with mild cognitive impairment reported that a phosphatidylserine-containing supplement improved several cognitive measures, especially short-term memory.
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A 2025 Frontiers in Nutrition study found that different supplemental choline forms produced distinct one-carbon metabolite patterns, with genetic variation influencing the response.
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A 2024 Nutrients study found that alpha-glycerylphosphorylcholine supplementation improved Stroop-test performance in healthy young men, reinforcing demand for fast-acting choline formats in cognitive products.
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A 2025 Perspective on future directions in choline says key questions remain around brain, liver, and cardiometabolic effects, highlighting ongoing demand for stronger biomarkers and more precise nutrition work.
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FDA's GRAS inventory now shows a no-questions response for a sunflower lecithin notice, adding a current U.S. reference point for buyers tracking source options and technical dossiers.
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Bunge says it has closed its acquisition of IFF's soy protein concentrate, lecithin, and crush assets, a move that strengthens scale in protein and phospholipid-adjacent ingredient supply.
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A CRN-backed U.S. Senate proposal would create a federal dietary supplement registry, keeping market attention on listing, traceability, and product-file readiness.
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Medella Springs says its new AddiVance formula is positioned for daily focus and attention support, adding another current phosphatidylserine use case in family-oriented supplement marketing.
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Midi Health's first supplement line includes a Daily Cortisol Support formula with phosphatidylserine, extending PS use into women 40+ hormone and stress-positioned products.
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A randomized trial of milk fat globule membrane phospholipids in older adults found no significant overall cognitive effect, though the high-dose group showed better subjective alertness during testing.
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A recent dry-eye study of sunflower lecithin supplementation reported no significant improvement versus placebo, offering a cautionary evidence point for phosphatidylcholine-rich positioning.
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A pediatric nutrition review argues that choline supply should be assessed more carefully across formulas, fortifiers, and supplements, keeping attention on phosphatidylcholine-linked ingredient design in early-life products.
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A 2025 meta-analysis supports further study of choline supplementation during or after alcohol-exposed pregnancies, keeping prenatal choline evidence in focus for specialized nutrition developers.
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A 2025 lecithin study in Chinese older adults and SAMP8 mice connects memory and muscle endpoints, widening interest in lecithin beyond standard emulsifier or choline-supply discussions.
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Wellex ha lanzado un suplemento en polvo que combina fosfatidilserina, citicolina y creatina, lo que refleja el uso continuo de PS en productos nutricionales de múltiples ingredientes.
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