Back to News

Ingredient news

PS Supplement Trial Reports Short-Term Memory Gains in MCI

By Nutranexa News |

A randomized placebo-controlled trial in Chinese older adults with mild cognitive impairment reported that a phosphatidylserine-containing supplement improved several cognitive measures, especially short-term memory.

Clinical memory-assessment room with phosphatidylserine supplement packs, note cards, and an older adult trial workstation

Nutranexa generated image

What Was Tested

A paper indexed by PubMed in January 2025 examined a food supplement containing phosphatidylserine in Chinese older adults with mild cognitive impairment using a randomized, double-blind, placebo-controlled design.

This is a clinically focused setting, so the study matters more for technical evidence mapping than for direct consumer claim copying.

What the Paper Reported

The PubMed summary says the supplement could improve different cognitive functions in the MCI group, especially short-term memory.

The same summary notes increases in serum n-3 PUFAs and neurotransmitter levels, with serum ALA described as a possible mediator.

Buyer Takeaway

Ingredient buyers should separate a disease-population trial from general-market claim use, but the paper is still a useful signal on dose framing and co-ingredient design in cognition products.

Studies like this also reinforce the value of documenting exactly what was in the tested formula rather than treating 'PS' as a uniform evidence category.

Sources